Huge Retroperitoneal Liposarcoma: A Case Report & Literature Review
DOI:
https://doi.org/10.48111/2022.01.09Keywords:
Retroperitoneal liposarcoma, Enbloc resectionAbstract
Retroperitoneal liposarcomas are amongst the commonest soft tissue sarcomas in the retroperitoneum. They can reach enormous sizes before presentation to a hospital. Contrast-enhanced CT scan is of utmost importance in estimating the location, extent, and depth of the malignancy. An image-guided biopsy can be of great help in the planning of treatment plans and in clinically equivocal cases. Complete Ro resection is of paramount importance in treating this aggressive disease entity. Radiotherapy and chemotherapy in the pre-operative stage can help in sensitive tumors. Molecular therapies are in the trial phase to strengthen treatment options. Here we present an interesting case, discuss its management and provide a literature review.
References
Tseng WW, Chen J, Patel D, et al. Multidisciplinary sarcoma tumor board: retroperitoneal liposarcoma. Chinese Clin Oncol. 2020;9(2):20-20. doi:10.21037/CCO.2020.02.08
Herzberg J, Niehaus K, Holl-Ulrich K, Honarpisheh H, Guraya SY, Strate T. Giant retroperitoneal liposarcoma: A case report and literature review. J Taibah Univ Med Sci. 2019;14(5):466. doi:10.1016/J.JTUMED.2019.08.005
Tyler R, Wanigasooriya K, Taniere P, et al. A review of retroperitoneal liposarcoma genomics. Cancer Treat Rev. 2020;86. doi:10.1016/J.CTRV.2020.102013
Dalal KM, Kattan MW, Antonescu CR, Brennan MF, Singer S. Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg. 2006;244(3):381-389. doi:10.1097/01.SLA.0000234795.98607.00
Matthyssens LE, Creytens D, Ceelen WP. Retroperitoneal liposarcoma: current insights in diagnosis and treatment. Front Surg. 2015;2. doi:10.3389/FSURG.2015.00004
Windham TC, Pisters PWT. Retroperitoneal sarcomas. Cancer Control. 2005;12(1):36-43. doi:10.1177/107327480501200105
Porpiglia AS, Reddy SS, Farma JM. Retroperitoneal Sarcomas. Surg Clin North Am. 2016;96(5):993-1001. doi:10.1016/j.suc.2016.05.009
Porter GA, Baxter NN, Pisters PWT. Retroperitoneal sarcoma: a population-based analysis of epidemiology, surgery, and radiotherapy. Cancer. 2006;106(7):1610-1616. doi:10.1002/CNCR.21761
Han HH, Choi KH, Kim DS, et al. Retroperitoneal Giant Liposarcoma. Korean J Urol. 2010;51(8):579. doi:10.4111/KJU.2010.51.8.579
Kopplin L, Kim J. Retroperitoneal sarcoma: a rare cause of intestinal perforation in two cases. J Surg Case Reports. 2011;2011(5):3. doi:10.1093/JSCR/2011.5.3
Ramu D, Manjunath S, Anuradh G. Recurrent Retroperitoneal Liposarcoma: a Case Report and Literature Review. Indian J Surg Oncol. 2018;9(4):640-643. doi:10.1007/S13193-018-0774-2
Gronchi A, Lo Vullo S, Fiore M, et al. Aggressive surgical policies in a retrospectively reviewed single-institution case series of retroperitoneal soft tissue sarcoma patients. J Clin Oncol. 2009;27(1):24-30. doi:10.1200/JCO.2008.17.8871
Dominguez E, Lopez de Cenarruzabeitia I, Martinez M, Rueda JC, Lede A, Barreiro E DS. Giant dedifferentiated retroperitoneal liposarcoma - PubMed. Int Surg. 2008;93(4):247-249. Accessed April 14, 2022. https://pubmed.ncbi.nlm.nih.gov/19731863/
Lewis JJ, Leung D, Woodruff JM, Brennan MF. Retroperitoneal soft-tissue sarcoma: analysis of 500 patients treated and followed at a single institution. Ann Surg. 1998;228(3):355. doi:10.1097/00000658-199809000-00008
Kumar V, Misra S, Chaturvedi A. Retroperitoneal Sarcomas- A Challenging Problem. Indian J Surg Oncol. 2012;3(3):215. doi:10.1007/S13193-012-0152-4
Haas RLM, Bonvalot S, Miceli R, et al. Radiotherapy for retroperitoneal liposarcoma: A report from the Transatlantic Retroperitoneal Sarcoma Working Group. Cancer. 2019;125(8):1290-1300. doi:10.1002/CNCR.31927
Van Houdt WJ, Zaidi S, Messiou C, Thway K, Strauss DC, Jones RL. Treatment of retroperitoneal sarcoma: current standards and new developments. Curr Opin Oncol. 2017;29(4):260-267. doi:10.1097/CCO.0000000000000377
Haddox CL, Riedel RF. Recent advances in the understanding and management of liposarcoma. Fac Rev. 2021;10. doi:10.12703/R/10-1
Bonvalot S, Rivoire M, Castaing M, et al. Primary retroperitoneal sarcomas: a multivariate analysis of surgical factors associated with local control. J Clin Oncol. 2009;27(1):31-37. doi:10.1200/JCO.2008.18.0802
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