Nonfunctioning Pancreatic Neuroendocrine Tumour (NF-PNET) Presenting as Pancreatitis: A Rare Clinical Association
Keywords:Nonfunctioning Pancreatic Neuroendocrine Tumour, Pancreatitis, Whipple procedure, pancreaticoduodenectomy
IMPORTANCE Pancreatic neuroendocrine tumors are relatively rare tumors. They make up 2-5% of all pancreatic tumors. It is important to diagnose them in the early stage. They are found incidentally or if malignant with either epigastric pain or distant metastasis. Very rarely PNETs may present with pancreatitis. Only 30 such cases have been reported previously which did present with focal pancreatitis. Here we present such a rare case.
CASE PRESENTATION A 51-year-old female presented with a history of recurrent epigastric pain for the past 4 years. On Ultrasound and CT scan, a 2x2cm well-defined mass in the head of the pancreas was observed. The findings were confirmed with a CT scan. A modified Whipple procedure was done and a histopathological report showed WHO grade – I neuroendocrine tumor with chromogramin positive tumor cells.
DISCUSSION & CONCLUSION The association between neuroendocrine tumors and pancreatitis is very rare hence neuroendocrine tumors should be considered as a differential diagnosis while dealing with such cases.
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